“The only risk of failure is promotion.”
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Home is pretty utopian.
The best plan now is to have as many bosses as possible. I call it boss diversity. If you work for a company and you have one boss and that boss doesn't like you or wants to get rid of you, you're in trouble. But if you work for yourself, you have lots of bosses, who are your customers, and if a few of them decide they don't like you, that's okay.
Obviously there's not much options when you're a cartoonist - you pretty much either work at home or rent an office I guess, and working at home just seems easier.
Some of my best friends are Venture Capitalists, but let's face it, a hamster with Alzheimer's could make those kind of numbers. It's great work if you can get it.